Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial

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Insulin Resistance and Polycystic Ovary Syndrome.

BACKGROUND Insulin resistance and the associated compensatory hyperinsulinemia are common findings in women with PCOS, and may play a key role in this condition. METHODS In this article, we focused on the significance of insulin resistance in PCOS, reviewing the available literature on epidemiology, pathogenesis, pathophysiology and treatment of this condition. RESULTS It has been estimated...

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Effect of berberine on insulin resistance in women with polycystic ovary syndrome: study protocol for a randomized multicenter controlled trial

BACKGROUND Insulin resistance and hyperinsulinemia play a key role in the pathogenesis of polycystic ovary syndrome (PCOS), which is characterized by hyperandrogenism, ovulatory dysfunction, and presence of polycystic ovaries on pelvic scanning. Insulin resistance is significantly associated with the long-term risks of metabolic syndrome and cardiovascular disease. Berberine has effects on insu...

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Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.

OBJECTIVE Limited data are available for evaluating the effects of oral carnitine supplementation on weight loss and metabolic profiles of women with polycystic ovary syndrome (PCOS). This study was designed to determine the effects of oral carnitine supplementation on weight loss, and glycaemic and lipid profiles in women with PCOS. DESIGN, PATIENTS AND MEASUREMENTS In a prospective, randomi...

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High Serum Ferritin Concentrations in Polycystic Ovary Syndrome Is Not Related to Insulin Resistance

OBJECTIVE: Some data are available on the association between components of the insulin resistance syndrome and serum ferritin. Insulin resistance is observed in patients with polycystic ovary syndrome (PCOS) We hypothesize that body iron stores might be increased in these women. MATERIALS AND METHODS: Two hundred and six people (103 PCOS patients and 103 healthy women who were matched for a...

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Selective insulin resistance in the polycystic ovary syndrome.

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenemia that is amplified by insulin in the presence of resistance to insulin's action to stimulate glucose uptake in muscle and fat. To explore the mechanisms for this paradox, we examined the metabolic and mitogenic actions of insulin and insulin-like growth factor I (IGF-I) in cultured skin fibroblasts from PCOS (n = 16) and cont...

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ژورنال

عنوان ژورنال: Journal of Obstetrics and Gynaecology Research

سال: 2015

ISSN: 1341-8076

DOI: 10.1111/jog.12907